I use an Osprey, but after talking with some long term nomads I have changed my mind and will be switching before my next trip.
Don't get me wrong I love my Osprey, but I've found that mine doesn't have the pockets I need to stay organized and is more suited to hiking / a lot of walking. I guess I'm a lazy backpacker
when I'm doing a lot of walking it's not with all my luggage.
Allow me to introduce you to https://www.tombihn.com/collections/travel-bags
. My friends who have been DN-ing for 7 years are now solely using this brand after trying a lot.